https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Patterns and predictors of gestational weight gain in Addis Ababa, Central Ethiopia: a prospective cohort study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48709 Wed 29 Mar 2023 17:26:24 AEDT ]]> Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45150 Wed 26 Oct 2022 19:29:23 AEDT ]]> Diet quality and 6-year risk of overweight and obesity among mid-age Australian women who were initially in the healthy weight range https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29593 Wed 24 Nov 2021 15:52:55 AEDT ]]> Diet quality and 10-year healthcare costs by BMI categories in the mid-age cohort of the Australian Longitudinal Study on Women's Health https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35627 Wed 24 Nov 2021 15:52:05 AEDT ]]> Influence of body mass index on subjective and objective measures of pain, functional impairment, and health-related quality of life in lumbar degenerative disc disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33325 Wed 19 Jan 2022 15:17:19 AEDT ]]> Characterizing gestational weight gain in a cohort of Indigenous Australian women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33045 Wed 17 Nov 2021 16:29:02 AEDT ]]> Genetic risk score mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30306 Wed 15 Dec 2021 16:09:28 AEDT ]]> Differential benefit of adjuvant docetaxel-based chemotherapy in patients with early breast cancer according to baseline body mass index https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47165 2) was categorized as follows: 18.5 to < 25, lean; 25 to < 30, overweight; and ≥ 30, obese. Disease-free survival (DFS) was the primary endpoint, and overall survival (OS) was the secondary endpoint. A second-order interaction was assessed among treatment, BMI, and estrogen receptor (ER) status. Results: There was no difference in DFS or OS according to BMI in the non-docetaxel group, while reduced DFS and OS were observed with increasing BMI category in the docetaxel group. Adjusted hazard ratios for DFS and OS were, respectively, 1.12 (95% CI, 0.98 to 1.50; P = .21) and 1.27 (95% CI, 1.01 to 1.60; P = .04) for overweight versus lean groups and were 1.32 (95% CI, 1.08 to 1.62; P = .007) and 1.63 (95% CI, 1.27 to 2.09; P < .001), respectively, for obese versus lean groups. Similar results were obtained when considering ER-negative and ER-positive tumors separately and when considering only patients who received a relative dose intensity ≥ 85% for docetaxel. A joint modifying role of BMI and ER status on treatment effect was evident for DFS (adjusted P = .06) and OS (adjusted P = .04). Conclusion: This retrospective analysis of a large adjuvant trial highlights a differential response to docetaxel according to BMI, which calls for a body composition–based re-evaluation of the risk-benefit ratio of the use of taxanes in breast cancer. These results now must be confirmed in additional series.]]> Wed 14 Dec 2022 15:49:14 AEDT ]]> Lower Vegetable Variety and Worsening Diet Quality Over Time Are Associated With Higher 15-Year Health Care Claims and Costs Among Australian Women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49321 Wed 13 Mar 2024 08:52:20 AEDT ]]> Patterns of diet, physical activity, sitting and sleep are associated with socio-demographic, behavioural, and health-risk indicators in adults https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35855 Wed 11 Dec 2019 14:37:23 AEDT ]]> Dysmotility symptoms are independently associated with weight change: a population-based study of Australian adults https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26276 Wed 11 Apr 2018 16:11:50 AEST ]]> How accurate is web-based self-reported height, weight, and body mass index in young adults? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13783 Wed 11 Apr 2018 16:00:09 AEST ]]> Paediatric obesity, inflammation & asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12524 Wed 11 Apr 2018 15:30:28 AEST ]]> Transsulfuration pathway thiols and methylated arginines: the hunter community study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14939 Wed 11 Apr 2018 15:21:27 AEST ]]> Body mass index and incident hospitalisation for cardiovascular disease in 158 546 participants from the 45 and Up Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21379 -2, including 3096 for ischaemic heart disease (IHD), 1373 for stroke, 411 for peripheral vascular disease (PVD) and 320 for heart failure. The adjusted HR of hospitalisation for all CVD diagnoses combined increased significantly with increasing BMI (P(trend) <0.0001)). The HR of IHD hospitalisation increased by 23% (95% confidence interval (95% CI): 18-27%) per 5 kg m-2 increase in BMI (compared to BMI 20.0-22.49 kg m-2, HR (95% CI) for BMI categories were: 22.5-24.99=1.25 (1.08-1.44); 25-27.49=1.43 (1.24-1.65); 27.5-29.99=1.64 (1.42-1.90); 30-32.49=1.63 (1.39-1.91) and 32.5-50=2.10 (1.79-2.45)). The risk of hospitalisation for heart failure showed a significant, but nonlinear, increase with increasing BMI. No significant increase was seen with above-normal BMI for stroke or PVD. For other specific classifications of CVD, HRs of hospitalisation increased significantly with increasing BMI for: hypertension; angina; acute myocardial infarction; chronic IHD; pulmonary embolism; non-rheumatic aortic valve disorders; atrioventricular and left bundle-branch block; atrial fibrillation and flutter; aortic aneurysm; and phlebitis and thrombophlebitis. Conclusion: The risk of hospitalisation for a wide range of CVD subtypes increases with relatively fine increments in BMI. Obesity prevention strategies are likely to benefit from focusing on bringing down the mean BMI at the population level, in addition to targeting those with a high BMI.]]> Wed 11 Apr 2018 14:09:31 AEST ]]> Diet-induced weight loss in obese children with asthma: a randomized controlled trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14519 Wed 11 Apr 2018 13:27:14 AEST ]]> The 40-Something randomized controlled trial to prevent weight gain in mid-age women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13787 Wed 11 Apr 2018 13:25:27 AEST ]]> Weight retention in the postpartum period https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13216 Wed 11 Apr 2018 13:09:26 AEST ]]> Book review: Gendering European History 1780—1920 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14733 Wed 11 Apr 2018 10:23:10 AEST ]]> Dietary pattern transitions, and the associations with BMI, waist circumference, weight and hypertension in a 7-year follow-up among the older Chinese population: a longitudinal study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29961 Wed 11 Apr 2018 09:38:40 AEST ]]> Asthma in reproductive-aged women with polycystic ovary syndrome and association with obesity https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31352 Wed 10 Nov 2021 15:04:27 AEDT ]]> Stress increases the risk of type 2 diabetes onset in women: a 12-year longitudinal study using causal modelling https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32912 Wed 09 Mar 2022 16:02:02 AEDT ]]> Obesity, polycystic ovary syndrome and breastfeeding: an observational study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30011 Wed 09 Feb 2022 15:54:28 AEDT ]]> Sex differences in obesity, dietary habits, and physical activity among urban middle-class Bangladeshis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43500 Wed 07 Feb 2024 17:15:59 AEDT ]]> Association between body mass index and estimated glomerular filtration rate in patients with chronic kidney disease of unknown aetiology in Sri Lanka https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37163 2) had the lowest BMI compared to those with normal eGFR. The majority affected were male farmers. The severity of the disease was inversely associated with BMI values and had a higher prevalence of smoking and alcohol consumption. In addition, those who consume water from household dug wells had significantly lower eGFR (p < 0.0001). A linear regression analysis revealed a significant positive association between lower eGFR and lower BMI (p < 0.001). We hypothesised that the low BMI in those with CKDu may have increased susceptibility to develop CKDu, in the presence of exposure to multiple nephrotoxins and adverse conditions.]]> Wed 07 Apr 2021 20:21:25 AEST ]]> Relationships between nutritional knowledge, obesity, and sleep disorder severity https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25450 Wed 02 Mar 2022 14:23:51 AEDT ]]> Postterm pregnancy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13861 Tue 24 Aug 2021 14:00:21 AEST ]]> Vimentin is required for normal accumulation of body fat https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48562 Vim-/-) display phenotypes reflecting reduced levels of cell activation and ability to counteract stress, for example, decreased reactivity of astrocytes after neurotrauma, decreased migration of astrocytes and fibroblasts, attenuated inflammation and fibrosis in lung injury, delayed wound healing, impaired vascular adaptation to nephrectomy, impaired transendothelial migration of lymphocytes and attenuated atherosclerosis. To address the role of vimentin in fat accumulation, we assessed the body weight and fat by dual-energy X-ray absorptiometry (DEXA) in Vim-/- and matched wildtype (WT) mice. While the weight of 1.5-month-old Vim-/- and WT mice was comparable, Vim-/- mice showed decreased body weight at 3.5, 5.5 and 8.5 months (males by 19-22%, females by 18-29%). At 8.5 months, Vim-/- males and females had less body fat compared to WT mice (a decrease by 24%, p < 0.05, and 33%, p < 0.0001, respectively). The body mass index in 8.5 months old Vim-/- mice was lower in males (6.8 vs. 7.8, p < 0.005) and females (6.0 vs. 7.7, p < 0.0001) despite the slightly lower body length of Vim-/- mice. Increased mortality was observed in adult Vim-/- males. We conclude that vimentin is required for the normal accumulation of body fat.]]> Tue 21 Mar 2023 15:44:53 AEDT ]]> Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44630 Tue 18 Oct 2022 12:11:18 AEDT ]]> Potential roles of Helicobacter pylori treatment, body mass index and waist circumference in the causation of erosive esophagitis: a randomized clinical trial (HEROES-GERD) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41979 Tue 16 Aug 2022 15:48:32 AEST ]]> BMI trajectory and subsequent risk of type 2 diabetes among middle-aged women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46311 Tue 15 Nov 2022 11:17:49 AEDT ]]> The role of intergenerational educational mobility and household wealth in adult obesity: evidence from wave 2 of the World Health Organization's Study on global AGEing and adult health https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44251 Tue 11 Oct 2022 12:28:43 AEDT ]]> Accuracy of parent-reported child height and weight and calculated body mass index compared with objectively measured anthropometrics: secondary analysis of a randomized controlled trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35681 Thu 28 Oct 2021 13:04:55 AEDT ]]> Adiposity is related to decrements in cardiorespiratory fitness in obese and normal-weight children https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23234 2peak ) were assessed. Analyses were adjusted for socioeconomic status (SES). Results: Higher percent fat was inversely associated with VO2peak normalized for mass (r = -0.780, P < 0.001) even after controlling for physical activity (r = -0.673, P < 0.001). While higher percent fat was also inversely associated with VO2peak normalized for FFM, this was only significant in males (r = -0.247, P = 0.004) and did not persist after controlling for physical activity (r = -0.059 P = 0.526). Compared with normal-weight children, obese children had higher absolute VO2peak, lower VO2peak corrected for mass (P = 0.009) and lower VO2peak corrected for FFM (P = 0.041) that did not persist after controlling for SES (P = 0.086). Conclusion: Obesity-related inefficiencies in CRF were evident. Higher adiposity was associated with poorer CRF relative to mass, irrespective of physical activity levels. However, low physical activity levels may be responsible for associations between adiposity and CRF relative to FFM seen in boys, indicating the importance of encouraging physical activity.]]> Thu 28 Oct 2021 13:02:48 AEDT ]]> Adolescents with type 1 diabetes can achieve glycemic targets on intensive insulin therapy without excessive weight gain https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51868 75 mmol/mol (>9.0%) in 2004 (p = .873), 2010 (p = .10) or 2016 (p = .630). Mean HbA1c decreased from 2004 to 2016 in the 10-13 year (69 mmol/mol (8.4%) vs. 57 mmol/mol (7.4%), p = <.001) and 14-17 year group (72 mmol/mol (8.7%) vs. 63 mmol/mol (7.9%), p = <.001). Prior to the implementation of MDI and CSII in 2004 only 10% of 10-13 year olds and 8% of 14-17 year olds achieved the international target for glycemic control (HbA1c 53 mmol/mol [<7.0%]). In 2016, this increased to 31% of 10-13 year olds and 21% of 14-17 year olds. CONCLUSIONS: BMI-SDS did not increase with the change to intensive insulin therapy despite a doubling in the number of adolescents achieving the recommended glycemic target of <7.0% (53 mmol/mol). HbA1c was not associated with weight gain.]]> Thu 21 Sep 2023 10:24:57 AEST ]]> Food insecurity partially mediates associations between social disadvantage and body composition among older adults in India: results from the study on global AGEing and adult health (SAGE) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33979 Thu 21 Oct 2021 12:52:18 AEDT ]]> Rural-urban disparities in stage of breast cancer at diagnosis in Australian women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29674 Thu 21 Oct 2021 12:51:43 AEDT ]]> Rapidly increasing prevalence of overweight and obesity in older Ghanaian adults from 2007-2015: evidence from WHO-SAGE Waves 1&2 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37424 Thu 12 Nov 2020 18:13:51 AEDT ]]> Multi-site randomized controlled trial of a child-centered physical activity program, a parent-centered dietary-modification program, or both in overweight children: the HIKCUPS study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9451 Sat 24 Mar 2018 10:44:31 AEDT ]]> An examination of the relationships between dietary behaviours with physical activity and obesity in adults with type2 diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7017 Sat 24 Mar 2018 08:38:05 AEDT ]]> Prevalence and magnitude of classical risk factors for stroke in a cohort of 5092 chinese steelworkers over 13.5 years of follow-up https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1947 Sat 24 Mar 2018 08:33:19 AEDT ]]> Predictors of post-partum weight retention in a prospective longitudinal study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15986 Sat 24 Mar 2018 08:23:40 AEDT ]]> Trends in anthropometry and severity of sleep-disordered breathing over two decades of diagnostic sleep studies in an Australian adult sleep laboratory https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10954 = 40) increased from 3% in 1987 to 16% in 2007. Median AHI progressively increased from 1992-1995 to 2004-2007 (from 65 events/h to 143 events/h, P < 0001), indicating increasing disease severity. Over the same period, for every unit increase in BMI, AHI increased by 5 5 events/h for men and by 2 8 events/h for women. About 80% of the observed variance in AHI over this period was attributable to variance in BMI. Conclusion: There is a continuing trend towards increasing body weight and BMI in people undergoing diagnostic sleep studies. Our data do not support the hypothesis that increased accessibility to diagnostic services and increased awareness of sleep disorders are resulting in a decline in disease severity. These findings are consistent with the premise that worsening severity in sleep-disordered breathing is primarily attributable to increasing obesity.]]> Sat 24 Mar 2018 08:14:14 AEDT ]]> Children's intake of fruit and selected energy-dense nutrient-poor foods is associated with fathers' intake https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12314 0.05). Children’s intakes of fruit and some energy-dense nutrient-poor foods but not vegetables were related to their father’s intakes. The targeting of fathers should be tested in experimental studies as a potential strategy to improve child and family eating habits.]]> Sat 24 Mar 2018 08:11:35 AEDT ]]> Body mass index and survival in men and women aged 70 to 75 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10696 Sat 24 Mar 2018 08:09:54 AEDT ]]> Obesity and risk of recurrence or death after adjuvant endocrine therapy with letrozole or tamoxifen in the Breast International Group 1-98 trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21393 = 30 kg/m²) had slightly poorer OS (hazard ratio [HR] = 1.19; 95% CI, 0.99 to 1.44) than patients with normal BMI (< 25 kg/m²), whereas no trend in OS was observed in overweight (BMI 25 to < 30 kg/m²) versus normal-weight patients (HR = 1.02; 95% CI, 0.86 to 1.20). Treatment-by-BMI interactions were not statistically significant. The HRs for OS comparing obese versus normal BMI were HR = 1.22 (95% CI, 0.93 to 1.60) and HR = 1.18 (95% CI, 0.91 to 1.52) in the letrozole and tamoxifen groups, respectively. Conclusion: There was no evidence that the benefit of letrozole over tamoxifen differed according to patients' BMI.]]> Sat 24 Mar 2018 08:05:04 AEDT ]]> Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20559 Sat 24 Mar 2018 08:02:35 AEDT ]]> Knee extensor strength differences in obese and healthy-weight 10-to 13-year-olds https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19495 N = 107 (51 female, 56 male)] and healthy-weight [N = 132 (56 female, 76 male)] 10- to 13-year-old children. Body mass index, body composition (dual energy X-ray absorptiometry), isokinetic/isometric peak KE torques (dynamometry) and physical activity (accelerometry) were assessed. Results revealed that compared with their healthy-weight peers, obese children had higher absolute KE torques (P ≤ 0.005), equivocal KE torques when allometrically normalized for fat-free mass (FFM) (P ≥ 0.448) but lower relative KE torques when allometrically normalized for body mass (P ≤ 0.008). Adjustments for maternal education, income and accelerometry had little impact on group differences, except for isometric KE torques relative to body mass which were no longer significantly lower in obese children (P ≥ 0.013, not significant after controlling for multiple comparisons). Percent body fat was inversely related to KE torques relative to body mass (r = −0.22 to −0.35, P ≤ 0.002), irrespective of maternal education, income or accelerometry. In conclusion, while obese children have higher absolute KE strength and FFM, they have less functional KE strength (relative to mass) available for weight-bearing activities than healthy-weight children. The finding that FFM-normalized KE torques did not differ suggests that the intrinsic contractile properties of the KE muscles are unaffected by obesity. Future research is needed to see if deficits in KE strength relative to mass translate into functional limitations in weight-bearing activities.]]> Sat 24 Mar 2018 08:02:19 AEDT ]]> Are the national guidelines for health behaviour appropriate for older Australians?: evidence from the Men, Women and Ageing Project https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17283 Sat 24 Mar 2018 08:01:48 AEDT ]]> Outdoor time is associated with physical activity, sedentary time, and cardiorespiratory fitness in youth https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20907 6500 counts/min). Secondary outcomes included sedentary behavior, cardiorespiratory fitness, overweight status, and blood pressure. Results: Among the 306 youth studied, those who reported spending most/all of their after-school time outdoors (n = 120) participated in more MVPA (61.0 ± 24.3 vs 39.9 ± 19.1 min/day; adjusted P < .001), were more likely to achieve the recommended minimum 60 min/day of MVPA (aOR 2.8; 95% CI, 1.3-6.4), spent less time in sedentary activities (539 ± 97 min/day vs 610 ± 146 min/day; adjusted P < .001), and had higher cardiorespiratory fitness (49 ± 5 vs 45 ± 6 mL/kg/min; adjusted P < .001) than youth who reported no time outdoors (n = 52). No differences in overweight/obesity or blood pressure were observed across the groups. Conclusions: Time spent outdoors is positively associated with MVPA and cardiorespiratory fitness in youth and negatively associated with sedentary behavior. Experimental trials are needed to determine whether strategies designed to increase time spent outdoors exert a positive influence on physical activity and fitness levels in youth.]]> Sat 24 Mar 2018 07:57:55 AEDT ]]> Musculoskeletal pain in obese compared with healthy-weight children https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21320 P=0.006), pain in more locations (P≤0.005), and a higher prevalence of lower limb pain (60% vs. 52% respectively, P=0.012) than healthy-weight children. Significant relationships were observed between body mass index and total pain locations (P≤0.004, unadjusted and adjusted) and worst pain intensity (P≤0.009, adjusted for socioeconomic status/accelerometry). There were no significant relationships between percent body fat and pain variables (unadjusted/adjusted analyses, P = 0.262 to 1.0). Discussion: Obesity in children was associated with increased overall and lower limb musculoskeletal pain, for which body mass index was a stronger predictor than adiposity. Clinicians treating obese children should screen for pain and prescribe exercise programs that take their symptoms into account.]]> Sat 24 Mar 2018 07:52:51 AEDT ]]> The association of body mass index with health-related quality of life: an exploratory study in a multiethnic Asian population https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5337 Sat 24 Mar 2018 07:45:55 AEDT ]]> Increasing central adiposity: the Nepean longitudinal study of young people aged 7-8 to 12-13 y https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:270 Sat 24 Mar 2018 07:43:02 AEDT ]]> Obesity in pregnancy: implications for foetal and postnatal growth https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28616 Sat 24 Mar 2018 07:38:56 AEDT ]]> Association between sports participation, motor competence and weight status: a longitudinal study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29980 Sat 24 Mar 2018 07:37:38 AEDT ]]> The stability of 'food addiction' as assessed by the Yale Food Addiction Scale in a non-clinical population over 18-months https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26150 Sat 24 Mar 2018 07:35:26 AEDT ]]> Lower activity levels are related to higher plantar pressures in overweight children https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25714 Sat 24 Mar 2018 07:33:28 AEDT ]]> Genetic studies of body mass index yield new insights for obesity biology https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27460 −8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.]]> Sat 24 Mar 2018 07:32:44 AEDT ]]> Hot flushes and night sweats symptom profiles over a 17-year period in mid-aged women: the role of hysterectomy with ovarian conservation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24995 Sat 24 Mar 2018 07:09:54 AEDT ]]> Diet quality, dietary inflammatory index and body mass index as predictors of response to adjunctive N-acetylcysteine and mitochondrial agents in adults with bipolar disorder: a sub-study of a randomised placebo-controlled trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39177 n = 133). Participants received 16 weeks adjunctive treatment of either placebo or N-acetylcysteine-alone or a combination of mitochondrial-enhancing nutraceuticals including N-acetylcysteine (combination treatment). Participants were followed up 4 weeks post-treatment discontinuation (Week 20). Diet was assessed by the Cancer Council Victoria Dietary Questionnaire for Epidemiological Studies, Version 2, converted into an Australian Recommended Food Score to measure diet quality, and energy-adjusted dietary inflammatory index score to measure inflammatory potential of diet. Body mass index was also measured. Generalised estimating equation models were used to assess whether diet quality, energy-adjusted dietary inflammatory index score and/or body mass index were predictors of response to significant outcomes of the primary trial: depression symptoms, clinician-rated improvement and functioning measures. Results: In participants taking combination treatment compared to placebo, change in depression scores was not predicted by Australian Recommended Food Score, dietary inflammatory index or body mass index scores. However, participants with better diet quality (Australian Recommended Food Score) reported reduced general depression and bipolar depression symptoms (p = 0.01 and p = 0.03, respectively) and greater clinician-rated improvement (p = 0.02) irrespective of treatment and time. Participants who had a more anti-inflammatory dietary inflammatory index had less impairment in functioning (p = 0.01). Combination treatment may attenuate the adverse effects of pro-inflammatory diet (p = 0.03) on functioning. Participants with lower body mass index who received combination treatment (p = 0.02) or N-acetylcysteine (p = 0.02) showed greater clinician-rated improvement. Conclusion: These data support a possible association between diet (quality and inflammatory potential), body mass index and response to treatment for bipolar depression in the context of a nutraceutical trial. The results should be interpreted cautiously because of limitations, including numerous null findings, modest sample size and being secondary analyses.]]> Mon 23 May 2022 14:53:36 AEST ]]> Systemic inflammation mediates the detrimental effects of obesity on asthma control https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47551 Mon 23 Jan 2023 12:29:49 AEDT ]]> Parent-reported compared with researcher-measured child height and weight: impact on body mass index classification in Australian pre-school aged children https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53543 0.8 = “excellent”; 0.61-0.8 = “good”; 0.41-0.60 = “moderate”; 0.21 and 0.4 = “fair [weak]”; <0.2 = “poor”). Results: Overall, 89 children were included (mean age: 4.7 years; 59.5% female). The mean difference between parent-reported and researcher-measured data were small (BMI z-score: mean difference −0.01 [95% CI: −0.45 to 0.44]). There was “fair/weak” agreement between parent-categorised child BMI compared with researcher-measured data (Cohen's Kappa 0.24 [95% CI: 0.06 to 0.42]). Agreement was poor (Cohen's kappa <0.2) for female children, when reported by fathers or by parents with a BMI > 25 kg/m2. Conclusion: There was “fair/weak” agreement between parent-reported and measured estimates of child weight status. So What?: Parent's report of weight and height may be a weak indicator of adiposity at the level of individuals however it may be useful for aggregate estimates.]]> Mon 04 Dec 2023 15:58:46 AEDT ]]> Diet quality is lower among adults with a BMI ≥40 kg m⁻² or a history of weight loss surgery https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37085 −2 and weight loss surgery reported the lowest diet quality (ARFS 31 ± 10 points). Conclusion: Diet quality was highest among those with high nutrition knowledge and lower BMI. Those with a BMI ≥ 40 kg·m−2, particularly those with past weight loss surgery reported the lowest diet quality, despite comparable levels of nutrition knowledge. It remains unclear which factors explain the variation in diet quality in the weight loss surgery group and this deserves further attention given the growing popularity of weight loss surgery.]]> Fri 28 May 2021 12:17:09 AEST ]]> Impact of Embedding High-Intensity Interval Training in Schools and Sports Training on Children and Adolescent's Cardiometabolic Health and Health-Related Fitness: Systematic Review and Meta-Analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53237  .05). Risk of bias results were variable (low = 8, some concerns = 9, and high = 7). Conclusion: Our findings suggest that embedding high-intensity interval training in schools and sports training can facilitate improvements in some aspects of cardiometabolic health and fitness in children and adolescents.]]> Fri 17 Nov 2023 16:20:02 AEDT ]]> Obesity, the new childhood disability? An umbrella review on the association between adiposity and physical function https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41822 Fri 12 Aug 2022 12:52:22 AEST ]]> Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41815 Fri 12 Aug 2022 12:45:25 AEST ]]> Associations of muscle-strengthening exercise with overweight, obesity, and depressive symptoms in adolescents: Findings from 2019 Youth Risk Behavior Surveillance system https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51521 Fri 08 Sep 2023 12:03:15 AEST ]]>